See CJ Evans' articles in Biofuels Digest:

Here's How the U.S. Can Outcompete its Competitors - Part 1: 
To Make America Great Again the U.S. Government Needs to Invest More in Innovations
Here's How the U.S. Can Outcompete its Competitors - Part 2: 
Supercharging  U.S. Innovation - How to Bring Technologies to Market Faster

In Defense of the U.S. Department of Energy's Transformative Grant and Loan Guarantee ProgramsPart 1: Generating Revenues for the U.S. Treasury & Advancing U.S. Global CompetitivenessPart 2: Advancing Innovations from Early-Stage Promise to the Threshold of Commercialization

 Development Capital, the Lifeblood of Every New Initiative, Is Much Too Hard to Obtain